Table of Contents
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Volume 8 Issue 7, Jul 2023

Article
RPS15 interacted with IGF2BP1 to promote esophageal squamous cell carcinoma development via recognizing m6A modification
Yahui Zhao,Yang Li,Rui Zhu,Riyue Feng,Heyang Cui,Xiao Yu,Furong Huang,Ruixiang Zhang,Xiankai Chen,Lei Li,Yinghui Chen,Yuhao Liu,Jinhua Wang,Guanhua Du &…Zhihua Liu  ORCID: orcid.org/0000-0003-4242-033X 
https://doi.org/10.1038/s41392-023-01428-1
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CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors
Jing Zhang,Fang Cai,Renbin Lu,Xiaoliang Xing,Lu Xu  ORCID: orcid.org/0000-0003-3231-041X,Kunyang Wu,Zishan Gong,Qing Zhang,Yun Zhang,Mengen Xing,Weihong Song  ORCID: orcid.org/0000-0001-9928-889X &…Jia-Da Li 
https://doi.org/10.1038/s41392-023-01431-6
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Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits
Liying Chen,Yingwei Xu,Heming Cheng,Zhongxia Li,Nanxi Lai,Menghan Li,Yeping Ruan,Yang Zheng,Fan Fei,Cenglin Xu  ORCID: orcid.org/0000-0002-4337-3777,Jiao Ma,Shuang Wang,Yan Gu,Feng Han,Zhong Chen  ORCID: orcid.org/0000-0003-4755-9357 &…Yi Wang  ORCID: orcid.org/0000-0002-1350-2961 
https://doi.org/10.1038/s41392-023-01433-4
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A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy
Yanru Zhao,Huaping Li,Hengzhi Du,Zhongwei Yin,Mengying He,Jiahui Fan,Xiang Nie,Yang Sun,Huiying Hou,Beibei Dai,Xudong Zhang,Yuanyuan Cai,Kunying Jin,Nan Ding,Zheng Wen,Jiang Chang  ORCID: orcid.org/0000-0001-8551-9458,Chen Chen  ORCID: orcid.org/0000-0001-5080-9383 &…Dao Wen Wang  ORCID: orcid.org/0000-0002-9774-3980 
https://doi.org/10.1038/s41392-023-01434-3
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Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium
Yang Peng  ORCID: orcid.org/0000-0002-2113-5858,Shi-ying Chen,Zhao-ni Wang,Zi-qing Zhou,Jing Sun,Gui-an Zhang,Jia Li,Lei Wang,Jin-cun Zhao  ORCID: orcid.org/0000-0003-2515-5589,Xiao Xiao Tang  ORCID: orcid.org/0000-0002-3383-0989,De-Yun Wang &…Nan-shan Zhong 
https://doi.org/10.1038/s41392-023-01511-7
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Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease
Boyuan Ma,Anji Ju,Shaosen Zhang  ORCID: orcid.org/0000-0003-0010-1445,Qi An,Siran Xu,Jie Liu,Li Yu,Yan Fu &…Yongzhang Luo 
https://doi.org/10.1038/s41392-023-01437-0
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Low levels of neutralizing antibodies against XBB Omicron subvariants after BA.5 infection
Jingyun Yang,Weiqi Hong  ORCID: orcid.org/0000-0003-1668-2301,Hong Lei,Cai He,Wenwen Lei,Yanan Zhou,Tingmei Zhao  ORCID: orcid.org/0000-0003-0979-1374,Aqu Alu  ORCID: orcid.org/0000-0002-9981-0120,Xuelei Ma,Jiong Li  ORCID: orcid.org/0000-0002-3742-630X,Li Yang,Zhenling Wang,Wei Wang  ORCID: orcid.org/0000-0001-7788-1895,Guangwen Lu  ORCID: orcid.org/0000-0001-7568-592X,Guobo Shen,Shuaiyao Lu  ORCID: orcid.org/0000-0003-1675-9735,Guizhen Wu,Huashan Shi &…Xiawei Wei  ORCID: orcid.org/0000-0002-6513-6422 
https://doi.org/10.1038/s41392-023-01495-4
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Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis
Sheng-yuan Zhang,Qiu-ping Xu,Li-na Shi,Shih-wen Li,Wei-hong Wang,Qing-qing Wang,Liao-xun Lu,Hui Xiao  ORCID: orcid.org/0000-0001-5304-243X,Jun-hong Wang,Feng-ying Li,Yin-ming Liang  ORCID: orcid.org/0000-0001-9174-4037,Si-tang Gong,Hao-ran Peng,Zheng Zhang  ORCID: orcid.org/0000-0002-3544-1389 &…Hong Tang 
https://doi.org/10.1038/s41392-023-01438-z
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TRIM28 promotes the escape of gastric cancer cells from immune surveillance by increasing PD-L1 abundance
Xiaoxiao Ma,Shuqin Jia,Gangjian Wang,Min Liang,Ting Guo,Hong Du,Sisi Li,Xiaomei Li,Longtao Huangfu,Jianping Guo  ORCID: orcid.org/0000-0002-8158-0101,Xiaofang Xing &…Jiafu Ji 
https://doi.org/10.1038/s41392-023-01450-3
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Extracellular matrix-derived mechanical force governs breast cancer cell stemness and quiescence transition through integrin-DDR signaling
Cong Li,Shi Qiu,Xiaohan Liu,Fengzhu Guo  ORCID: orcid.org/0000-0002-0478-9315,Jingtong Zhai,Zhijun Li,Linghui Deng,Liming Ge,Haili Qian,Lu Yang &…Binghe Xu 
https://doi.org/10.1038/s41392-023-01453-0
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Efficacy, safety and pharmacokinetics of Unecritinib (TQ-B3101) for patients with ROS1 positive advanced non-small cell lung cancer: a Phase I/II Trial
Shun Lu  ORCID: orcid.org/0000-0001-8833-7262,Hongming Pan,Lin Wu,Yu Yao,Jianxing He,Yan Wang,Xiuwen Wang,Yong Fang,Zhen Zhou,Xicheng Wang,Xiuyu Cai,Yan Yu,Zhiyong Ma,Xuhong Min,Zhixiong Yang,Lejie Cao,Huaping Yang,Yongqian Shu,Wu Zhuang,Shundong Cang,Jian Fang,Kai Li,Zhuang Yu,Jiuwei Cui,Yang Zhang,Man Li,Xinxuan Wen,Jie Zhang,Weidong Li,Jianhua Shi,Xingxiang Xu,Diansheng Zhong,Tao Wang &…Jiajia Zhu 
https://doi.org/10.1038/s41392-023-01454-z
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Letter
Murine studies and expressional analyses of human cardiac pericytes reveal novel trajectories of SARS-CoV-2 Spike protein-induced microvascular damage
Elisa Avolio  ORCID: orcid.org/0000-0003-4801-8480,Prashant K. Srivastava,Jiahui Ji,Michele Carrabba,Christopher T. W. Tsang  ORCID: orcid.org/0000-0003-3394-6604,Yue Gu,Anita C. Thomas  ORCID: orcid.org/0000-0002-3792-2653,Kapil Gupta  ORCID: orcid.org/0000-0002-2115-3503,Imre Berger,Costanza Emanueli &…Paolo Madeddu 
https://doi.org/10.1038/s41392-023-01489-2
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Neutralizing antibodies against SARS-CoV-2 virus after vaccination in patients with neurofibromatosis type 1
Qiao-ling Ruan,Zhi-chao Wang  ORCID: orcid.org/0000-0002-5859-4193,Cheng-jiang Wei,Wei Wang,Qing-luan Yang,Jing Wu,Yan-min Wan  ORCID: orcid.org/0000-0001-5027-9423,Ling-ling Ge,Wen-hong Zhang &…Qing-feng Li  ORCID: orcid.org/0000-0001-7822-618X 
https://doi.org/10.1038/s41392-023-01498-1
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Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis
Yiming Chao  ORCID: orcid.org/0000-0002-3188-7551,Yang Xiang,Jiashun Xiao,Weizhong Zheng,Mo R. Ebrahimkhani,Can Yang  ORCID: orcid.org/0000-0002-4407-3055,Angela Ruohao Wu,Pentao Liu,Yuanhua Huang  ORCID: orcid.org/0000-0003-3124-9186 &…Ryohichi Sugimura  ORCID: orcid.org/0000-0001-5701-3628 
https://doi.org/10.1038/s41392-023-01455-y
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A new treatment for sarcoma extracted from combination of miRNA deregulation and gene association rules
José Manuel García-Heredia,Marco Pérez,Eva M. Verdugo-Sivianes,María M. Martínez-Ballesteros,Sara M. Ortega-Campos &…Amancio Carnero  ORCID: orcid.org/0000-0003-4357-3979 
https://doi.org/10.1038/s41392-023-01470-z
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Predicting assembly mode of membraneless organelles by a FRET-based crowding sensor
Feng Chen  ORCID: orcid.org/0000-0002-0182-5712,Siyuan Shen,Xu Cao,Liang Zhang,Lunxu Liu,Daoke Yang,Yunyu Shi,Wei He,Xuebiao Yao &…Dan Liu 
https://doi.org/10.1038/s41392-023-01435-2
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Oral administration of D-glucosamine confers broad-spectrum protection against human coronaviruses including SARS-CoV-2
Qi Qi,Qi Chen,Yumei Dong,Kun Wang,Jialu Wang,Guiming Jin,Aiping Zheng,Rong Zhang,Yongqiang Deng  ORCID: orcid.org/0000-0002-2306-1039,Yuhuan Li,Chengfeng Qin &…Xiaotao Duan 
https://doi.org/10.1038/s41392-023-01483-8
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Neural stem cell-derived extracellular vesicles mitigate Alzheimer’s disease-like phenotypes in a preclinical mouse model
Ge Gao,Congcong Li,Yizhao Ma,Zhanping Liang,Yun Li,Xiangyu Li,Shengyang Fu,Yi Wang,Xiaohuan Xia &…Jialin C. Zheng  ORCID: orcid.org/0000-0003-2286-0151 
https://doi.org/10.1038/s41392-023-01436-1
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Cyclin L1 controls cardiomyocyte proliferation and heart repair after injury
Rui Gong,Xinlu Gao,Yu Liu,Yifu Shen,Zuke Jiang,Xiuxiu Wang,Naufal Zagidullin,Wenya Ma,Ning Wang &…Benzhi Cai 
https://doi.org/10.1038/s41392-023-01444-1
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Integrated genetic and epigenetic analysis reveals DNA repair alterations in multifocal hepatocellular carcinoma
Yi-Hong Ling,Meng-Ni Liu,Yi-Xin Yin,Zhong-Guo Zhou,Jie-Wei Chen,Wei Wei,Jing-Ping Yun,Dan Xie  ORCID: orcid.org/0000-0003-2242-3138,Rong-Ping Guo &…Mu-Yan Cai  ORCID: orcid.org/0000-0002-4646-4391 
https://doi.org/10.1038/s41392-023-01446-z
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Review Article
Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection
Peiran Chen  ORCID: orcid.org/0000-0002-4367-5468,Mandi Wu,Yaqing He,Binghua Jiang &…Ming-Liang He 
https://doi.org/10.1038/s41392-023-01510-8
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Inflammation and aging: signaling pathways and intervention therapies
Xia Li,Chentao Li,Wanying Zhang,Yanan Wang  ORCID: orcid.org/0000-0003-4947-8665,Pengxu Qian  ORCID: orcid.org/0000-0001-5636-6704 &…He Huang  ORCID: orcid.org/0000-0002-2723-1621 
https://doi.org/10.1038/s41392-023-01502-8
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T cells in health and disease
Lina Sun,Yanhong Su,Anjun Jiao,Xin Wang &…Baojun Zhang  ORCID: orcid.org/0000-0002-7786-4304 
https://doi.org/10.1038/s41392-023-01471-y
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Spinal cord injury: molecular mechanisms and therapeutic interventions
Xiao Hu,Wei Xu,Yilong Ren,Zhaojie Wang,Xiaolie He,Runzhi Huang,Bei Ma,Jingwei Zhao,Rongrong Zhu &…Liming Cheng 
https://doi.org/10.1038/s41392-023-01477-6
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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
Yun Zhang,Huaqiu Chen,Ran Li,Keenan Sterling &…Weihong Song  ORCID: orcid.org/0000-0001-9928-889X 
https://doi.org/10.1038/s41392-023-01484-7
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Research Highlight
A metabolite of the gut microbiota: a facilitator of chemotherapy efficacy in cancer
Byungsuk Kwon 
https://doi.org/10.1038/s41392-023-01506-4
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Harnessing the potential of spatial multiomics: a timely opportunity
Xuexin Li  ORCID: orcid.org/0000-0001-5824-9720 
https://doi.org/10.1038/s41392-023-01507-3
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A new mission for an old anti-cancer drug: harnessing hepatocyte-specific metabolic pathways against liver tumors
Weiting Liao,Diego F. Calvisi  ORCID: orcid.org/0000-0002-6038-8567 &Xin Chen  ORCID: orcid.org/0000-0002-9588-0164 
https://doi.org/10.1038/s41392-023-01513-5
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New case of HIV cure: joined forces of haploidentical stem cells and HLA-mismatched cord blood
David Peterhoff 
https://doi.org/10.1038/s41392-023-01514-4
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The sugar-free paradox: cardiometabolic consequences of erythritol
Kalliopi Pafili &Michael Roden  ORCID: orcid.org/0000-0001-8200-6382 
https://doi.org/10.1038/s41392-023-01504-6
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Phase separating Rho: a widespread regulatory function of disordered regions in proteins revealed in bacteria
Eric Schumbera,Pablo Mier  ORCID: orcid.org/0000-0003-3663-2352 &Miguel A. Andrade-Navarro  ORCID: orcid.org/0000-0001-6650-1711 
https://doi.org/10.1038/s41392-023-01505-5
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CRISPRing the hypertrophic cardiomyopathy: correcting one pathogenic variant at a time
Junaid Afzal  ORCID: orcid.org/0000-0002-2877-234X & Kshitiz  ORCID: orcid.org/0000-0003-4241-9427 
https://doi.org/10.1038/s41392-023-01526-0
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Porous insights: IpaH7.8 reveals crystal-clear differences of gasdermins in mice and men
Friedrich Alexander von Samson-Himmelstjerna,Benedikt Kolbrink &Stefan Krautwald  ORCID: orcid.org/0000-0001-7768-2132 
https://doi.org/10.1038/s41392-023-01535-z
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