Table of Contents
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Volume 7 Issue 12, Dec 2022

Review Article
Monkeypox: epidemiology, pathogenesis, treatment and prevention
Yong Huang,Li Mu &Wei Wang  ORCID: orcid.org/0000-0001-7788-1895 
https://doi.org/10.1038/s41392-022-01215-4
Full Text | PDF | Abstract
Epigenetic regulation of aging: implications for interventions of aging and diseases
Kang Wang,Huicong Liu,Qinchao Hu,Lingna Wang,Jiaqing Liu,Zikai Zheng,Weiqi Zhang,Jie Ren,Fangfang Zhu &…Guang-Hui Liu  ORCID: orcid.org/0000-0001-9289-8177 
https://doi.org/10.1038/s41392-022-01211-8
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The Hippo signalling pathway and its implications in human health and diseases
Minyang Fu,Yuan Hu,Tianxia Lan,Kun-Liang Guan,Ting Luo &…Min Luo  ORCID: orcid.org/0000-0002-6875-7945 
https://doi.org/10.1038/s41392-022-01191-9
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Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
Jingjing Yang,Anthony Griffin  ORCID: orcid.org/0000-0003-0526-194X,Zhe Qiang &…Jie Ren 
https://doi.org/10.1038/s41392-022-01243-0
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Copper homeostasis and cuproptosis in health and disease
Liyun Chen,Junxia Min  ORCID: orcid.org/0000-0001-8099-6327 &Fudi Wang  ORCID: orcid.org/0000-0001-8730-0003 
https://doi.org/10.1038/s41392-022-01229-y
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Molecular mechanisms of exercise contributing to tissue regeneration
Jibao Chen,Ren Zhou,Ye Feng &…Lin Cheng 
https://doi.org/10.1038/s41392-022-01233-2
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Research Highlight
Fire up the pyre: inosine thermogenic signaling for obesity therapy
Nienke Willemsen  ORCID: orcid.org/0000-0003-1571-4236,Stefan Kotschi  ORCID: orcid.org/0000-0001-9857-6291 &Alexander Bartelt  ORCID: orcid.org/0000-0001-7840-3991 
https://doi.org/10.1038/s41392-022-01218-1
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Article
Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents
Zhiqing Li,Xiaosu Chen,Junyan Dan,Tianju Hu,Ye Hu,Shuxun Liu,Yangyang Chai,Yansong Shi,Jian Wu,Hailai Ni,Jiaqi Zhu,Yanfeng Wu,Nan Li,Yizhi Yu,Zhongfang Wang,Jincun Zhao  ORCID: orcid.org/0000-0003-2515-5589,Nanshan Zhong,Xianwen Ren,Zhongyang Shen &…Xuetao Cao 
https://doi.org/10.1038/s41392-022-01237-y
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A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis
Qizhi Ma,Xia He,Benxia Zhang,Fuchun Guo,Xuejin Ou,Qiyu Yang,Pei Shu,Yue Chen,Kai Li,Ge Gao,Yajuan Zhu,Diyuan Qin,Jie Tang  ORCID: orcid.org/0000-0001-8841-0781,Xiaoyu Li,Meng Jing,Jian Zhao,Zeming Mo,Ning Liu,Yao Zeng,Kexun Zhou,Mingyang Feng,Weiting Liao,Wanting Lei,Qiu Li,Dan Li &…Yongsheng Wang 
https://doi.org/10.1038/s41392-022-01198-2
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CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
Jiao Wu,Liang Chen,Chuan Qin  ORCID: orcid.org/0000-0002-6261-1232,Fei Huo,Xue Liang,Xu Yang,Kui Zhang,Peng Lin,Jiangning Liu,Zhuan Feng,Jiansheng Zhou,Zhuo Pei,Yatao Wang,Xiu-Xuan Sun,Ke Wang  ORCID: orcid.org/0000-0001-8913-7115,Jiejie Geng,Zhaohui Zheng,Xianghui Fu,Man Liu,Qingyi Wang,Zheng Zhang,Huijie Bian  ORCID: orcid.org/0000-0003-4690-4622,Ping Zhu &…Zhi-Nan Chen 
https://doi.org/10.1038/s41392-022-01230-5
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FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury
Letian Yang,Bo Wang,Fan Guo  ORCID: orcid.org/0000-0002-7329-5124,Rongshuang Huang,Yan Liang,Lingzhi Li,Sibei Tao,Ting Yin,Ping Fu  ORCID: orcid.org/0000-0002-3061-5925 &…Liang Ma  ORCID: orcid.org/0000-0001-8327-7969 
https://doi.org/10.1038/s41392-022-01254-x
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Letter
Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids
Yuxin Hou,Chang Li,Chaemin Yoon,On Wah Leung,Sikun You,Xiaoming Cui,Jasper Fuk-Woo Chan  ORCID: orcid.org/0000-0001-6336-6657,Duanqing Pei,Hoi Hung Cheung &…Hin Chu  ORCID: orcid.org/0000-0003-2855-9837 
https://doi.org/10.1038/s41392-022-01241-2
Full Text | PDF | Abstract