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Volume 6 Issue 1, Jan 2021

Article
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma
Qin Tang,Wan Li,Xiangjin Zheng,Liwen Ren,Jinyi Liu,Sha Li,Jinhua Wang &…Guanhua Du 
https://doi.org/10.1038/s41392-020-00288-3
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CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells
Ke Wang,Wei Chen,Zheng Zhang,Yongqiang Deng,Jian-Qi Lian,Peng Du,Ding Wei,Yang Zhang,Xiu-Xuan Sun,Li Gong,Xu Yang,Lei He,Lei Zhang,Zhiwei Yang  ORCID: orcid.org/0000-0001-6969-8177,Jie-Jie Geng,Ruo Chen,Hai Zhang,Bin Wang,Yu-Meng Zhu,Gang Nan,Jian-Li Jiang,Ling Li,Jiao Wu,Peng Lin,Wan Huang,Liangzhi Xie,Zhao-Hui Zheng,Kui Zhang,Jin-Lin Miao,Hong-Yong Cui,Min Huang,Jun Zhang  ORCID: orcid.org/0000-0002-9650-112X,Ling Fu,Xiang-Min Yang,Zhongpeng Zhao,Shihui Sun,Hongjing Gu,Zhe Wang,Chun-Fu Wang,Yacheng Lu,Ying-Ying Liu,Qing-Yi Wang,Huijie Bian,Ping Zhu &…Zhi-Nan Chen 
https://doi.org/10.1038/s41392-020-00426-x
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Longitudinal transcriptome analyses show robust T cell immunity during recovery from COVID-19
Hong-Yi Zheng,Min Xu,Cui-Xian Yang,Ren-Rong Tian,Mi Zhang,Jian-Jian Li,Xi-Cheng Wang,Zhao-Li Ding,Gui-Mei Li,Xiao-Lu Li,Yu-Qi He,Xing-Qi Dong,Yong-Gang Yao  ORCID: orcid.org/0000-0002-2955-0693 &…Yong-Tang Zheng  ORCID: orcid.org/0000-0001-5469-0324 
https://doi.org/10.1038/s41392-020-00457-4
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Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice
Xuekun Fu,Bo Zhou  ORCID: orcid.org/0000-0003-4213-726X,Qinnan Yan,Chu Tao,Lei Qin,Xiaohao Wu,Sixiong Lin  ORCID: orcid.org/0000-0001-7155-5044,Sheng Chen,Yumei Lai,Xuenong Zou,Zengwu Shao,Meiqing Wang,Di Chen,Wenfei Jin  ORCID: orcid.org/0000-0002-0028-3739,Youqiang Song,Huiling Cao,Ge Zhang &…Guozhi Xiao  ORCID: orcid.org/0000-0002-4269-2450 
https://doi.org/10.1038/s41392-020-00328-y
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CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
Junjie Xu,Lin Ji,Yuelong Liang,Zhe Wan,Wei Zheng  ORCID: orcid.org/0000-0003-1034-0757,Xiaomin Song,Kirill Gorshkov  ORCID: orcid.org/0000-0002-4652-8818,Qiming Sun  ORCID: orcid.org/0000-0003-4988-9886,Hui Lin,Xueyong Zheng,Jiang Chen,Ren-an Jin,Xiao Liang &…Xiujun Cai  ORCID: orcid.org/0000-0002-6457-0577 
https://doi.org/10.1038/s41392-020-00375-5
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m6A RNA methylation-mediated HNF3γ reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance
Tengfei Zhou,Shichao Li,Daimin Xiang,Junyu Liu,Wen Sun,Xiuliang Cui,Beifang Ning,Xiao Li,Zhuo Cheng,Weiqi Jiang,Cheng Zhang  ORCID: orcid.org/0000-0002-1857-3961,Xijun Liang,Liang Li,Xin Cheng,Liu Hui,Hongyang Wang  ORCID: orcid.org/0000-0002-4709-3334 &…Jin Ding 
https://doi.org/10.1038/s41392-020-00299-0
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STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17
Xiao-Yue Hong,Hua-Li Wan,Ting Li,Bing-Ge Zhang,Xiao-Guang Li,Xin Wang,Xiao Li,Qian Liu,Chong-Yang Chen,Ying Yang,Qun Wang,Shu-Peng Li,Hao Yu,Jian-Zhi Wang,Xi-Fei Yang &…Gong-Ping Liu  ORCID: orcid.org/0000-0001-8501-998X 
https://doi.org/10.1038/s41392-020-00290-9
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling
Yi Zheng,Meng-Wei Zhuang,Lulu Han,Jing Zhang,Mei-Ling Nan,Peng Zhan,Dongwei Kang  ORCID: orcid.org/0000-0001-9232-953X,Xinyong Liu,Chengjiang Gao &…Pei-Hui Wang  ORCID: orcid.org/0000-0001-6853-2423 
https://doi.org/10.1038/s41392-020-00438-7
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Combination of anti-PD-1 antibody with P-GEMOX as a potentially effective immunochemotherapy for advanced natural killer/T cell lymphoma
Jun Cai,Panpan Liu,Huiqiang Huang,Yajun Li,Shuyun Ma,Hui Zhou,Xiaopeng Tian,Yuchen Zhang,Yan Gao,Yi Xia,Xuanye Zhang,Hang Yang,Lirong Li &…Qingqing Cai 
https://doi.org/10.1038/s41392-020-00331-3
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Review Article
Methionine metabolism in chronic liver diseases: an update on molecular mechanism and therapeutic implication
Zhanghao Li,Feixia Wang,Baoyu Liang,Ying Su,Sumin Sun,Siwei Xia,Jiangjuan Shao,Zili Zhang,Min Hong,Feng Zhang &…Shizhong Zheng 
https://doi.org/10.1038/s41392-020-00349-7
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Fulminant myocarditis: a comprehensive review from etiology to treatments and outcomes
Weijian Hang,Chen Chen  ORCID: orcid.org/0000-0001-5080-9383,John M. Seubert &…Dao Wen Wang 
https://doi.org/10.1038/s41392-020-00360-y
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Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy
Jenna L. Carter,Katie Hege,Jay Yang,Hasini A. Kalpage  ORCID: orcid.org/0000-0002-5700-4884,Yongwei Su,Holly Edwards,Maik Hüttemann,Jeffrey W. Taub &…Yubin Ge  ORCID: orcid.org/0000-0002-8748-716X 
https://doi.org/10.1038/s41392-020-00361-x
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Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approaches
Yuefei Jin,Wangquan Ji,Haiyan Yang,Shuaiyin Chen,Weiguo Zhang &…Guangcai Duan 
https://doi.org/10.1038/s41392-020-00454-7
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Research Highlight
Inhibition of tumor autophagy: a strategy to improve anti-tumor immunity?
Andrew J. Freeman  ORCID: orcid.org/0000-0003-0040-5617,Emily J. Lelliott &Jane Oliaro 
https://doi.org/10.1038/s41392-020-00429-8
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Asynchronous actions of immune responses in COVID-19 patients
Yufang Shi,Guoqiang Zhou &Qing Li 
https://doi.org/10.1038/s41392-020-00424-z
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Letter
Characteristics of SARS-CoV-2-specific cytotoxic T cells revealed by single-cell immune profiling of longitudinal COVID-19 blood samples
Qing Xiong,Cheng Peng,Xiaomin Yan,Xueqi Yan,Lin Chen,Beicheng Sun &…Shiping Jiao 
https://doi.org/10.1038/s41392-020-00425-y
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Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection
Carlos Loucera  ORCID: orcid.org/0000-0001-9598-6965,Marina Esteban-Medina  ORCID: orcid.org/0000-0003-2632-9587,Kinza Rian,Matías M. Falco,Joaquín Dopazo  ORCID: orcid.org/0000-0003-3318-120X &…María Peña-Chilet  ORCID: orcid.org/0000-0002-6445-9617 
https://doi.org/10.1038/s41392-020-00417-y
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Cationic nanocarriers as potent adjuvants for recombinant S-RBD vaccine of SARS-CoV-2
Hong Lei,Aqu Alu  ORCID: orcid.org/0000-0002-9981-0120,Jingyun Yang,Cai He,Weiqi Hong,Zesheng Cheng  ORCID: orcid.org/0000-0001-7859-8813,Li Yang,Jiong Li,Zhenling Wang,Wei Wang  ORCID: orcid.org/0000-0001-7788-1895,Guangwen Lu  ORCID: orcid.org/0000-0001-7568-592X &…Xiawei Wei  ORCID: orcid.org/0000-0002-6513-6422 
https://doi.org/10.1038/s41392-020-00434-x
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Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality
Liting Chen,Gaoxiang Wang,Jiaqi Tan,Yang Cao,Xiaolu Long,Hui Luo,Qing Tang,Tiebin Jiang,Wei Wang &…Jianfeng Zhou 
https://doi.org/10.1038/s41392-020-00433-y
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