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Volume 4 Issue 1, Mar 2019

Article
Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning
Eliseos J. Mucaki,Jonathan Z. L. Zhao,Daniel J. Lizotte &…Peter K. Rogan  ORCID: orcid.org/0000-0003-2070-5254 
https://doi.org/10.1038/s41392-018-0034-5
Full Text | PDF | Abstract
Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma
Jihao Xu  ORCID: orcid.org/0000-0003-4063-0608,Wen-Hsin Chang,Lon Wolf R. Fong,Robert H. Weiss,Sung-Liang Yu &…Ching-Hsien Chen 
https://doi.org/10.1038/s41392-019-0035-z
Full Text | PDF | Abstract
Saikosaponin D suppresses enterovirus A71 infection by inhibiting autophagy
Chang Li,Lihong Huang,Wei Sun,Ying Chen,Ming-Liang He,Jianbo Yue  ORCID: orcid.org/0000-0001-6384-5447 &…Heather Ballard  ORCID: orcid.org/0000-0002-5818-8443 
https://doi.org/10.1038/s41392-019-0037-x
Full Text | PDF | Abstract
Review Article
Targeting growth hormone function: strategies and therapeutic applications
Man Lu,Jack U. Flanagan,Ries J. Langley  ORCID: orcid.org/0000-0001-8606-2197,Michael P. Hay  ORCID: orcid.org/0000-0002-7087-9087 &…Jo K. Perry  ORCID: orcid.org/0000-0002-4418-947X 
https://doi.org/10.1038/s41392-019-0036-y
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Targeting EGFR exon 20 insertion mutations in non-small cell lung cancer
Simon Vyse  ORCID: orcid.org/0000-0002-0582-2869 &Paul H. Huang 
https://doi.org/10.1038/s41392-019-0038-9
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Research Highlight
Deletion of the RNA-editing enzyme ADAR1A: new strategy to potentiate responses to PD-1 immune checkpoint blockade
Manni Wang &Xiawei Wei 
https://doi.org/10.1038/s41392-019-0039-8
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Targeting NR4As, a new strategy to fine-tune CAR-T cells against solid tumors
Feng Li &Yi Zhang 
https://doi.org/10.1038/s41392-019-0041-1
Full Text | PDF | Abstract