Deubiquitylating Nanog: novel role of USP21 in embryonic stem cell maintenance
Duanqing Pei
Recently, three groups independently identified ubiquitin-specific peptidase 21 (USP21) as an efficient deubiquitylase that reverses Nanog polyubiquitylation and stabilizes Nanog protein. In this preview, I have summarized the work of these three groups.